TR-FRET
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Explore more → **TR-FRET**
What is TR-FRET?
Time-Resolved Förster Resonance Energy Transfer (TR-FRET) is a homogeneous assay technology commonly used in drug discovery and other biological research. It combines FRET technology with time-resolved fluorescence detection. A donor molecule with a long-lived excited state transfers energy to an acceptor molecule if they are in close proximity. The signal is measured after a delay, reducing interference from short-lived background fluorescence.
What other technologies are related to TR-FRET?
TR-FRET Competitor Technologies
FP
Fluorescence Polarization (FP) is another fluorescence-based assay used for similar applications like binding assays, making it a direct competitor.
luminescence
Luminescence-based assays are used to measure molecular interactions and reporter gene expression and, as such, are a direct competitor for TR-FRET.
AlphaLISA
AlphaLISA is a bead-based proximity assay that, similar to TR-FRET, detects molecular interactions, making it a direct competitor.
ELISA
ELISA (Enzyme-Linked Immunosorbent Assay) is a plate-based assay used for detecting and quantifying substances like antibodies and proteins. While ELISA is typically used for quantification of proteins, it can be a competitor in certain applications where TR-FRET could be used similarly.
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TR-FRET Complementary Technologies
ITC
Isothermal Titration Calorimetry (ITC) measures the heat released or absorbed during a binding event, providing thermodynamic information that complements the binding affinity data obtained from TR-FRET.
MST
Microscale Thermophoresis (MST) measures changes in fluorescence upon temperature gradients to quantify binding affinities. It provides orthogonal validation of TR-FRET results.
SPR
Surface Plasmon Resonance (SPR) is a label-free technology that measures binding kinetics and affinity. It offers complementary information to TR-FRET, which is an endpoint assay.
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Which job functions commonly mention TR-FRET?
Chemist
0.1% of all Chemist jobs mention TR-FRET
View 80
jobs on Sumble
Scientist
0.1% of all Scientist jobs mention TR-FRET
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jobs on Sumble
Research Scientist
0.1% of all Research Scientist jobs mention TR-FRET
View 28
jobs on Sumble
Research Assistant
63 Research Assistant jobs mention TR-FRET
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jobs on Sumble
Researcher
102 Researcher jobs mention TR-FRET
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jobs on Sumble
Which organizations are mentioning TR-FRET?
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