IHC Insights | Sumble

What is IHC?

IHC, or Immunohistochemistry, is a laboratory technique that uses antibodies to detect specific antigens (proteins) in a tissue sample. These antigens can be used as biomarkers to identify cells or tissues. IHC is commonly used in diagnostic pathology for cancer diagnosis, identifying infectious agents, and understanding protein expression in research.

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What other technologies are related to IHC?

IHC Competitor Technologies

ISH

In situ hybridization is a competitor as it detects nucleic acid sequences directly in tissue sections, similar to IHC's protein detection.

mentioned alongside IHC in 65% (321) of relevant job posts

IF

Immunofluorescence is a competitor since it's an alternative method to visualize proteins in tissue sections using fluorescently labeled antibodies, similar to IHC but with fluorescence detection.

mentioned alongside IHC in 24% (334) of relevant job posts

Direct Immunofluorescent staining

Direct immunofluorescent staining is a competitor, representing a specific type of IF used for protein detection in tissues, similar to IHC.

mentioned alongside IHC in 100% (58) of relevant job posts

Immunoperoxidase staining

Immunoperoxidase staining represents a type of IHC that uses an enzyme to produce a visual signal. It is very similar to IHC so it's a direct competitor.

mentioned alongside IHC in 100% (58) of relevant job posts

RNAscope

RNAscope is a competitor as it is another method to see expression of RNA in tissue sections.

mentioned alongside IHC in 19% (83) of relevant job posts

DIF

Direct immunofluorescence is a competitor since it's an alternative method to visualize proteins in tissue sections using fluorescently labeled antibodies, similar to IHC but with fluorescence detection.

mentioned alongside IHC in 22% (60) of relevant job posts

MIF

Multiplex Immunofluorescence staining is a competitor since it's an alternative method to visualize multiple proteins in tissue sections using fluorescently labeled antibodies, similar to IHC but with fluorescence detection.

mentioned alongside IHC in 14% (56) of relevant job posts

ICC

Immunocytochemistry (ICC) is a competitor because it is used to examine the expression of proteins in cells, and is very similar to IHC.

mentioned alongside IHC in 3% (58) of relevant job posts

IHC Complementary Technologies

H&E

Hematoxylin and eosin staining provides general morphological context to tissue sections, often used alongside IHC to interpret protein expression within specific cellular structures.

mentioned alongside IHC in 27% (84) of relevant job posts

FISH

Fluorescence in situ hybridization can be used with IHC to observe both nucleic acid and protein expression at the same time in the same sample.

mentioned alongside IHC in 11% (182) of relevant job posts

WB

Western blotting is complementary as it can be used to validate antibody specificity and quantify protein levels, which can then be further investigated using IHC on tissue samples.

mentioned alongside IHC in 15% (127) of relevant job posts