H&E Insights | Sumble

What is H&E?

H&E stands for Hematoxylin and Eosin staining. It is the most commonly used staining method in histology and pathology. Hematoxylin stains acidic structures (like DNA and RNA in the nucleus) blue/purple, while Eosin stains basic structures (like proteins in the cytoplasm) pink. This allows pathologists to examine tissue samples under a microscope and identify cellular structures and abnormalities for diagnosis.

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What other technologies are related to H&E?

H&E Complementary Technologies

IHC

Immunohistochemistry (IHC) is a widely used technique in conjunction with H&E staining for detailed tissue analysis. IHC uses antibodies to bind to specific antigens in tissue sections, allowing for the visualization and localization of specific proteins within the tissue. H&E provides the general tissue morphology, while IHC highlights specific proteins, making them highly complementary.

mentioned alongside H&E in 3% (84) of relevant job posts

immunohistochemistry

Immunohistochemistry (IHC) is a widely used technique in conjunction with H&E staining for detailed tissue analysis. IHC uses antibodies to bind to specific antigens in tissue sections, allowing for the visualization and localization of specific proteins within the tissue. H&E provides the general tissue morphology, while IHC highlights specific proteins, making them highly complementary.

mentioned alongside H&E in 1% (107) of relevant job posts

immunofluorescence

Immunofluorescence (IF) is another antibody-based staining technique that can complement H&E staining. Like IHC, it allows for the detection of specific proteins within tissue sections. However, IF utilizes fluorescently labeled antibodies, which can offer higher sensitivity and the ability to detect multiple targets simultaneously. H&E provides the overall tissue context, while IF provides detailed protein localization information.

mentioned alongside H&E in 2% (59) of relevant job posts