CUT&RUN
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Explore more → **CUT&RUN**
What is CUT&RUN?
CUT&RUN (Cleavage Under Targets & Release Using Nuclease) is an epigenetic profiling strategy used to map DNA-protein interactions genome-wide. It uses antibody-targeted controlled cleavage by micrococcal nuclease (MNase) to selectively digest and release specific DNA fragments for sequencing. Compared to ChIP-seq, CUT&RUN offers higher resolution, lower background, and requires fewer cells.
What other technologies are related to CUT&RUN?
CUT&RUN Competitor Technologies
CUT&Tag
CUT&Tag is a competitor to CUT&RUN as it is an alternative chromatin profiling method using antibody-guided enzymatic cleavage.
ChIP-seq
ChIP-seq is a competitor to CUT&RUN as it is another method for mapping protein-DNA interactions, although CUT&RUN offers some advantages in terms of resolution and efficiency.
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CUT&RUN Complementary Technologies
ATAC-seq
ATAC-seq provides information about chromatin accessibility, which can complement CUT&RUN data that focuses on specific protein-DNA interactions. Combining ATAC-seq with CUT&RUN can provide a more comprehensive view of chromatin structure and regulation.
next-generation sequencing
Next-generation sequencing (NGS) is the underlying technology used to read the DNA fragments generated in a CUT&RUN experiment. NGS is essential for analyzing the results of CUT&RUN.
PCR
PCR may be used in the library preparation steps of CUT&RUN to amplify the DNA fragments prior to sequencing.
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Which job functions commonly mention CUT&RUN?
Bioinformatics
0.5% of all Bioinformatics jobs mention CUT&RUN
View 47
jobs on Sumble
Bioinformatician
0.5% of all Bioinformatician jobs mention CUT&RUN
View 15
jobs on Sumble
Biologist
0.1% of all Biologist jobs mention CUT&RUN
View 60
jobs on Sumble
Scientist
90 Scientist jobs mention CUT&RUN
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jobs on Sumble
Researcher
120 Researcher jobs mention CUT&RUN
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jobs on Sumble
Which organizations are mentioning CUT&RUN?
University of North Carolina at Chapel Hill
Educational Services
Dana-Farber Cancer Institute
Health Care and Social Assistance
Center for Genomic Regulation
Health Care and Social Assistance
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