Tangential flow filtration (TFF), also known as crossflow filtration, is a separation technique where the feed stream flows tangentially across the surface of a membrane. A portion of the feed stream passes through the membrane as permeate or filtrate, while the remainder, containing retained particles, is returned to the feed. TFF is commonly used for concentrating and purifying biomolecules, cell harvesting, and clarification of solutions in biotechnology, pharmaceuticals, and food processing.
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