surface plasmon resonance
**surface plasmon resonance**
What is surface plasmon resonance?
Surface plasmon resonance (SPR) is an optical phenomenon that occurs when polarized light strikes a thin metal film at the interface between two media, exciting surface plasmons. It is highly sensitive to changes in the refractive index at the metal surface, making it a powerful label-free technique for studying biomolecular interactions such as protein-protein, protein-ligand, and antibody-antigen binding. SPR is commonly used in biosensors for real-time monitoring of binding kinetics and affinity, as well as for detecting and quantifying various analytes.
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