liquid chromatography Insights

What is liquid chromatography?

Liquid chromatography (LC) is an analytical chemistry technique used to separate, identify, and quantify the components of a liquid mixture. The sample is dissolved in a mobile phase (a liquid) and forced through a stationary phase (a solid or a liquid supported on a solid). Components of the mixture interact differently with the stationary phase, causing them to elute at different times, allowing for separation and analysis. LC is widely used in pharmaceuticals, food chemistry, environmental monitoring, and various other fields.

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What other technologies are related to liquid chromatography?

liquid chromatography Competitor Technologies

gas chromatography

Gas chromatography is an alternative separation technique suitable for volatile and thermally stable compounds, whereas LC is used for non-volatile or thermally labile compounds.

mentioned alongside liquid chromatography in 14% (709) of relevant job posts

Ion Chromatography

Ion chromatography separates ions and polar molecules and can be used for similar purposes as some LC applications, especially for charged analytes. It is a form of liquid chromatography, however, typically utilizes conductivity for detection.

mentioned alongside liquid chromatography in 9% (152) of relevant job posts

capillary electrophoresis

Capillary electrophoresis is another separation technique that can be used as an alternative to LC, especially for charged molecules.

mentioned alongside liquid chromatography in 7% (189) of relevant job posts

gas chromatography/mass spectrometry

GC-MS is an alternative to LC-MS, used for volatile compounds.

mentioned alongside liquid chromatography in 7% (78) of relevant job posts

electrophoresis

Electrophoresis is a separation technique based on the movement of charged particles in an electric field and can be an alternative separation technique.

mentioned alongside liquid chromatography in 3% (92) of relevant job posts

GC

GC (Gas Chromatography) is an alternative separation technique suitable for volatile compounds.

mentioned alongside liquid chromatography in 0% (137) of relevant job posts

SDS-PAGE

SDS-PAGE (sodium dodecyl-sulfate polyacrylamide gel electrophoresis) is an electrophoresis technique used to separate proteins and peptides. Can be considered a competitor when separating proteins and large peptides.

mentioned alongside liquid chromatography in 1% (60) of relevant job posts

GC-MS

GC-MS is an alternative to LC-MS, used for volatile compounds.

mentioned alongside liquid chromatography in 1% (75) of relevant job posts