HPLC-MS/MS
What is HPLC-MS/MS?
HPLC-MS/MS (High-Performance Liquid Chromatography-Tandem Mass Spectrometry) is an analytical chemistry technique that combines the separation capabilities of HPLC with the detection capabilities of tandem mass spectrometry. It is used for identifying and quantifying specific compounds in complex mixtures with high sensitivity and selectivity. The HPLC separates the compounds, and the tandem mass spectrometer identifies and quantifies them by their mass-to-charge ratio, often involving fragmentation of the molecules for enhanced specificity.
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