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shRNA

shRNA

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What is shRNA?

shRNA (short hairpin RNA) is a type of RNA interference (RNAi) technology used to silence gene expression. It is a DNA sequence that is transcribed into a short RNA molecule with a tight hairpin turn that can be processed by the cell into siRNA. This siRNA then targets a specific mRNA molecule for degradation or translational repression, effectively reducing the production of the protein encoded by that mRNA. shRNA is commonly delivered using viral vectors, allowing for stable and long-term gene silencing in cells.

What other technologies are related to shRNA?

shRNA Competitor Technologies

siRNA is a similar RNA interference technology that also reduces gene expression. It's a direct alternative to shRNA.
mentioned alongside shRNA in 22% (231) of relevant job posts
CRISPR is a gene editing technology that can knock out genes, offering an alternative approach to gene silencing provided by shRNA.
mentioned alongside shRNA in 4% (243) of relevant job posts
CRISPR/Cas9 is a gene editing technology that can knock out genes, offering an alternative approach to gene silencing provided by shRNA.
mentioned alongside shRNA in 3% (120) of relevant job posts

shRNA Complementary Technologies

Western blotting can be used to verify the knockdown of protein expression after shRNA transfection. It confirms the effectiveness of shRNA.
mentioned alongside shRNA in 1% (95) of relevant job posts
Western blot is a technique to verify the knockdown of protein expression after shRNA transfection. It confirms the effectiveness of shRNA.
mentioned alongside shRNA in 1% (74) of relevant job posts
Cloning is required to generate shRNA constructs for delivery into cells.
mentioned alongside shRNA in 1% (55) of relevant job posts

Which organizations are mentioning shRNA?

Organization
Industry
Matching Teams
Matching People
shRNA
Novartis
Health Care and Social Assistance

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