PK/PD stands for Pharmacokinetics/Pharmacodynamics. Pharmacokinetics (PK) describes what the body does to the drug, including absorption, distribution, metabolism, and excretion (ADME). Pharmacodynamics (PD) describes what the drug does to the body, focusing on the drug's mechanism of action and its effects. PK/PD modeling is commonly used in drug development to predict drug concentrations in the body and their relationship to therapeutic and adverse effects, optimizing dosing regimens, and predicting drug efficacy and safety.
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