phage display Insights

What is phage display?

Phage display is a laboratory technique used to study protein-protein, protein-peptide, and protein-DNA interactions. In this technique, a gene encoding a protein of interest is inserted into a phage coat protein gene, causing the phage to 'display' the protein on its surface. These displayed proteins can then be used to screen for binding partners, such as antibodies, peptides, or DNA sequences. Phage display is commonly used for antibody discovery, directed evolution of proteins, and identifying peptide ligands for specific targets.

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What other technologies are related to phage display?

phage display Competitor Technologies

yeast display

Yeast display is an alternative method to phage display for displaying proteins or peptides on the surface of yeast cells for selection and directed evolution. Thus, they are directly competing technologies.

mentioned alongside phage display in 67% (108) of relevant job posts

phage display Complementary Technologies

SPR

Surface plasmon resonance (SPR) is a biophysical technique used to measure real-time binding affinities and kinetics. It is often used in conjunction with phage display to characterize the interaction between the selected phage clones and their target, thus acting as a complementary technique.

mentioned alongside phage display in 3% (78) of relevant job posts

ELISA

ELISA (Enzyme-Linked Immunosorbent Assay) is a plate-based assay technique designed for detecting and quantifying substances such as peptides, antibodies, and proteins. It is commonly used to validate the binding of phage clones selected through phage display to their target antigen, making it a complementary technique.

mentioned alongside phage display in 1% (174) of relevant job posts

flow cytometry

Flow cytometry is a technique used to analyze cells or particles based on their physical and chemical characteristics. It can be used to analyze and sort phage-displayed libraries or individual phage clones based on their binding to target cells or molecules, making it a complementary technique.

mentioned alongside phage display in 0% (82) of relevant job posts