Monolix Insights

What is Monolix?

Monolix is a software used for parameter estimation in nonlinear mixed-effects models. It is primarily employed in pharmacometrics to analyze population pharmacokinetic (PK) and pharmacodynamic (PD) data, enabling the characterization of drug behavior and variability within a population. It is used for model building, simulation, and clinical trial design, helping to optimize dosing regimens and predict treatment outcomes.

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What other technologies are related to Monolix?

Monolix Competitor Technologies

NONMEM

NONMEM is a primary competitor as it is a widely used software for nonlinear mixed-effects modeling, similar to Monolix.

mentioned alongside Monolix in 39% (803) of relevant job posts

Phoenix NLME

Phoenix NLME competes directly with Monolix, offering similar functionalities for pharmacokinetic and pharmacodynamic modeling using nonlinear mixed effects.

mentioned alongside Monolix in 66% (135) of relevant job posts

ADAPT

ADAPT is a software package for pharmacokinetic and pharmacodynamic modeling and is another competitor to Monolix.

mentioned alongside Monolix in 6% (74) of relevant job posts

Stan

Stan is a probabilistic programming language used for statistical modeling, including Bayesian PK/PD modeling, thus a competitor to Monolix.

mentioned alongside Monolix in 6% (51) of relevant job posts

Monolix Complementary Technologies

Simcyp

Simcyp is a mechanistic, physiologically-based pharmacokinetic (PBPK) modeling platform. While Monolix is primarily for statistical modeling (NLME), Simcyp provides a complementary approach that can inform the parameters and structure used in Monolix.

mentioned alongside Monolix in 31% (202) of relevant job posts

GastroPlus

GastroPlus is a PBPK modeling software focused on drug absorption and disposition. Like Simcyp, its mechanistic approach complements the statistical focus of Monolix.

mentioned alongside Monolix in 23% (122) of relevant job posts

PK-Sim

PK-Sim is also a PBPK modeling software. Models generated in PK-Sim can inform parameter values for NLME models developed in Monolix.

mentioned alongside Monolix in 43% (57) of relevant job posts