fragment analysis Insights

What is fragment analysis?

Fragment analysis is a molecular biology technique used to separate and detect DNA fragments based on their size. It's commonly used in microsatellite instability (MSI) analysis, short tandem repeat (STR) analysis for DNA fingerprinting, and mutation detection. The process typically involves PCR amplification of target regions, followed by separation of the fragments using capillary electrophoresis. The resulting data provides information about the size and quantity of each fragment.

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What other technologies are related to fragment analysis?

fragment analysis Competitor Technologies

Sanger sequencing

Sanger sequencing is a competitor because it is an alternative method for determining the nucleotide sequence of DNA, although generally lower throughput and higher cost than next-generation sequencing.

mentioned alongside fragment analysis in 7% (129) of relevant job posts

fragment analysis Complementary Technologies

real-time PCR

Real-time PCR (qPCR) can be used to validate NGS results, quantify target regions identified through sequencing, and prepare samples for sequencing.

mentioned alongside fragment analysis in 1% (60) of relevant job posts

PCR

PCR is complementary as it is often used for targeted amplification of DNA regions prior to sequencing to increase sensitivity.

mentioned alongside fragment analysis in 0% (126) of relevant job posts

qPCR

qPCR (quantitative PCR) is complementary because it can be used to validate NGS results and quantify specific sequences identified through sequencing.

mentioned alongside fragment analysis in 0% (52) of relevant job posts