UPLC/HPLC Insights

What is UPLC/HPLC?

UPLC (Ultra Performance Liquid Chromatography) and HPLC (High Performance Liquid Chromatography) are both liquid chromatography techniques used to separate, identify, and quantify components in a liquid sample. HPLC uses higher particle sizes and lower pressures, making it more robust and versatile for a wider range of applications. UPLC uses smaller particle sizes and higher pressures, resulting in faster separations, higher resolution, and increased sensitivity. Both techniques are widely used in pharmaceutical, food science, environmental, and chemical industries for quality control, research, and development.

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What other technologies are related to UPLC/HPLC?

UPLC/HPLC Competitor Technologies

GC

Gas chromatography (GC) is a chromatographic technique used for separating and analyzing compounds that can be vaporized without decomposition. It competes with UPLC/HPLC as an analytical separation technique, although each is better suited for different types of analytes (GC for volatile compounds, UPLC/HPLC for non-volatile or thermally labile compounds).

mentioned alongside UPLC/HPLC in 0% (117) of relevant job posts

UPLC/HPLC Complementary Technologies

Empower software

Empower is chromatography data system (CDS) software used for data acquisition, processing, and reporting of UPLC/HPLC results. It is essential for operating and analyzing data from UPLC/HPLC systems.

mentioned alongside UPLC/HPLC in 8% (56) of relevant job posts

dissolution

Dissolution testing measures the rate and extent a drug product dissolves, and is often coupled with UPLC/HPLC to quantify the amount of dissolved drug. The HPLC is used to measure the concentration of analyte in the dissolution media. The dissolution itself is not a competitor but complementary.

mentioned alongside UPLC/HPLC in 3% (60) of relevant job posts

SEC

Size exclusion chromatography (SEC) is a type of chromatography that separates molecules based on their size. It can be used as a complementary technique for UPLC/HPLC, especially for analyzing polymers, proteins, and other large molecules. It provides information about the molecular weight distribution of a sample before or after further analysis by UPLC/HPLC.

mentioned alongside UPLC/HPLC in 2% (51) of relevant job posts