What is Starfish?

Starfish is a technology that refers to a microscopy technique used for spatially resolving RNA transcripts within cells and tissues. It allows for the visualization of gene expression patterns at a subcellular level, providing insights into cellular function, organization, and interactions. Starfish uses a combinatorial labeling approach where specific RNA sequences are labeled with fluorescent probes that can be sequentially imaged, allowing researchers to identify and quantify multiple RNA transcripts simultaneously.