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RFdiffusion

RFdiffusion

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What is RFdiffusion?

RFdiffusion (Rose Diffusion) is a computational method used for protein design. It leverages diffusion models, similar to those used in image generation, to 'hallucinate' or design novel protein structures and sequences. Users can specify constraints or desired properties, and RFdiffusion generates proteins that satisfy those requirements. This technology is commonly used to design proteins with specific functions, such as binding to a target molecule or catalyzing a specific reaction, as well as scaffolds for targeted protein degradation.

What other technologies are related to RFdiffusion?

RFdiffusion Complementary Technologies

ProteinMPNN is a protein sequence design algorithm that can be used with RFdiffusion. It helps refine and optimize the sequences generated by RFdiffusion, improving the likelihood of successful protein folding and function. Thus, it complements RFdiffusion.
mentioned alongside RFdiffusion in 60% (62) of relevant job posts
AlphaFold is a protein structure prediction tool. While RFdiffusion generates protein structures, AlphaFold can be used to validate or refine these structures, ensuring they are physically realistic and likely to fold correctly. It is a tool to help validate RFdiffusion results.
mentioned alongside RFdiffusion in 16% (88) of relevant job posts

Which organizations are mentioning RFdiffusion?

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RFdiffusion
Epoch Biodesign
Scientific and Technical Services

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