What is PDX?

PDX is a generic abbreviation that can refer to multiple things, making it difficult to provide a specific description without further context. It commonly refers to Patient-Derived Xenografts. Patient-Derived Xenografts (PDX) are animal models, typically mice, that are engrafted with tissue or cells from a human patient. These models are used in cancer research and drug development to study tumor growth, metastasis, and response to therapy. This allows researchers to test the effectiveness of drugs in a preclinical setting using models that closely mimic the patient's tumor.