patch clamp
**patch clamp**
What is patch clamp?
Patch clamp is a laboratory technique in electrophysiology used to study ionic currents in individual cells, or small patches of cell membrane. It allows researchers to control the voltage across the cell membrane and measure the resulting current, or conversely, to control the current and measure the resulting voltage. It is commonly used to study the function of ion channels, which are pore-forming membrane proteins that allow ions to pass through the cell membrane, and to investigate the electrical properties of excitable cells such as neurons and muscle fibers. The technique involves using a glass micropipette to form a tight seal with a small patch of the cell membrane, allowing for precise control and measurement of electrical activity.
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