What is Nanopore?

Nanopore sequencing is a third-generation DNA sequencing technology that works by threading a single strand of DNA or RNA through a tiny pore (nanopore). As the molecule passes through the nanopore, it causes changes in electrical current that are unique to each base (A, T, C, G). By measuring these changes, the sequence of the molecule can be determined. It's commonly used for long-read sequencing, which is useful for de novo genome assembly, resolving structural variations, and sequencing complex regions of the genome.