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gel electrophoresis

gel electrophoresis

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What is gel electrophoresis?

Gel electrophoresis is a laboratory method used to separate mixtures of DNA, RNA, or proteins according to their size and charge. An electric field is applied to a gel matrix, causing the molecules to migrate through the gel at different rates. Smaller molecules move faster and farther than larger molecules. It's commonly used for analyzing DNA fragments, confirming the presence of specific proteins, and purifying biomolecules.

What other technologies are related to gel electrophoresis?

gel electrophoresis Competitor Technologies

DNA sequencing determines the nucleotide sequence and can provide information about DNA fragment size and identity, sometimes replacing the need for gel electrophoresis.
mentioned alongside gel electrophoresis in 9% (229) of relevant job posts
Capillary electrophoresis is an alternative method for separating molecules by size and charge, often offering higher resolution and automation compared to gel electrophoresis.
mentioned alongside gel electrophoresis in 7% (198) of relevant job posts
Sequence analysis, especially when combined with bioinformatics, can be used to predict fragment sizes and identify DNA fragments instead of using gel electrophoresis.
mentioned alongside gel electrophoresis in 16% (80) of relevant job posts

gel electrophoresis Complementary Technologies

PCR amplifies DNA fragments before gel electrophoresis for better visualization and analysis.
mentioned alongside gel electrophoresis in 8% (3.4k) of relevant job posts
Northern (RNA) and Western (protein) blotting use gel electrophoresis as a separation step before analysis.
mentioned alongside gel electrophoresis in 99% (245) of relevant job posts
DNA extraction is often performed to obtain DNA samples that are then separated by gel electrophoresis.
mentioned alongside gel electrophoresis in 13% (361) of relevant job posts

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