What is ELSD?

ELSD stands for Evaporative Light Scattering Detector. It is a universal detector used in liquid chromatography (LC) for compounds that lack a strong UV chromophore or are difficult to detect by other methods. The mobile phase is evaporated, and the resulting non-volatile analyte particles scatter light, which is then detected. It is commonly used for the analysis of sugars, lipids, and polymers.