Cas9 Insights | Sumble

What is Cas9?

Cas9 is an RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immune system in Streptococcus pyogenes. Cas9 unwinds DNA and cuts both strands, guided by an RNA sequence complementary to the target DNA. It is commonly used in gene editing to precisely modify DNA sequences within living organisms, enabling researchers to delete, insert, or replace specific genes.

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What other technologies are related to Cas9?

Cas9 Competitor Technologies

CRISPR

CRISPR is a gene editing technology that uses the Cas9 enzyme. While Cas9 is often associated with CRISPR, other CRISPR systems exist that utilize different Cas enzymes or mechanisms, making them alternatives or competitors.

mentioned alongside Cas9 in 3% (181) of relevant job posts

Cas9 Complementary Technologies

PCR

PCR (Polymerase Chain Reaction) is a technique used to amplify specific DNA sequences. It can be used in conjunction with Cas9 for applications such as validating gene edits or preparing DNA for Cas9-mediated editing.

mentioned alongside Cas9 in 0% (91) of relevant job posts

flow cytometry

Flow cytometry is a technique used to analyze cells and particles based on their physical and chemical characteristics. It can be used to analyze the results of Cas9 based gene editing by measuring expression of target genes.

mentioned alongside Cas9 in 0% (60) of relevant job posts